The Circulatory System Essay Example

The Circulatory System Essay Example The Circulatory System Paper The Circulatory System Paper General Functions   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The circulatory system is the body’s main transport network and cooling system (De Graff, 1998). The human body needs many external substances to survive. We need air, food, and water. However, these substances are not readily absorbed by the body through initial intake. For example, food that is eaten and digested is not yet used to fuel the body’s billions of cells. The nutrients that have been processed need to be transported to each cell in the body in order for them to be used. This is one of the jobs of the circulatory system. The circulatory system is tasked with carrying the important substances that the body needs where they are needed (Hillendale Health, 2007). Furthermore, the system is also responsible for carrying some of the wastes from the cells such as carbon dioxide, away from the cells to be expelled by the body (Delos Johnson, 2006). This cycle of carrying nutrients to body cells and carrying wastes from th em is a way by which the system contributes to the maintenance of physiological homeostasis. Another way that it contributes to homeostasis is by helping maintain the temperature of the body. Without oxygen to burn, the cells in the body will become cold and eventually die (Delos Johnson, 2006). Thus, oxygenated blood carries oxygen to the cells and releases it in order to maintain homeostatic temperature. Last but not the least, the circulatory system also maintains homeostasis by fighting off outside threats that have infiltrated the body. White blood cells which also travel through the system fight back diseases and help keep the body healthy and they need the circulatory system for them to be able to reach the places in the body where particular bacteria are doing damage (Delos Johnson, 2007). Interactions with other organ systems   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   When we eat food or drink water, it enters our body through our digestive system and is processed in the stomach. Afterwards, the processed food is transported through the small intestines where it is further digested. The small intestine’s inner walls are covered with microscopic finger-like projections called villi which are primarily responsible for taking the nutrients from the digested food and transferring them to the bloodstream where they are carried to the rest of the body (Maton et. al., 1993). Thus, the digestive system and the circulatory system work closely together to nourish the body with food and drink. The circulatory system also works closely with the respiratory system. We take in air through our nose and from there it travels to our lungs. From there, pulmonary arteries which are a part of the circulatory system carries oxygen-depleted blood to absorb more oxygen while releasing the carbon dioxide that it has accumulated from the cells that it delivered nutrients to (Maton et. al., 1993). Of course, the circulatory system takes blood containing nutrients and oxygen to other organ systems of the body in order to enable them to continue functioning. The blood carries nutrients to our muscles, our sensory organs, our brain, and all other parts of our body that need it (Maton, 2003). Parts and functions The Heart   It is a powerful muscle that pumps the blood through the entire circulatory system (Hillendale Health, 2007). The Blood It is the main substance that flows throughout the circulatory system. There are red blood cells and white blood cells that both travel through the circulatory system (Hillendale Health, 2007). Plasma which is the liquid part of the blood carries both these blood cells through the system (Hillendale Health, 2007). The red blood cells carry nutrients from the small intestine and oxygen from the lungs to the cells all over the body (Hillendale Health, 2007). They are also the ones that carry carbon dioxide away from body cells and back to the lungs to be released as waste (Hillendale Health, 2007). The white blood cells travel to areas where harmful germs are infecting body cells and fight those foreign elements to keep the body healthy (Hillendale Health, 2007). There are also platelets found in the bloodstream which acts to help stop bleeding whenever the body gets wounded (Hillendale Health, 2007). For example, whenever we cut ourselves on some sharp object and bleed, the platelets stick to where we cut ourselves and attract more platelets to do the same. This plugs out the wound so that the bleeding stops. The Blood Vessels The blood vessels are the tubes where the blood passes through. There are three types of blood vessels which are arteries, veins, and capillaries (Hillendale Health, 2007). The arteries are blood vessels that carrying oxygenated blood away from the heart while veins carry blood back to the heart (Hillendale Health, 2007). Capillaries are very tiny blood vessels that serve as connections between arteries and veins (Hillendale Health, 2007). The Heart: A closer look   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The human heart is found in the middle of the thorax with its largest part slightly situated to the left just beneath the breastbone (Maton et. al., 1993). It is a mesh of muscle cells that are joined together by contiguous cytoplasmic bridges (Maton et. al., 1993). Tissues found on the heart’s walls are unique because they have qualities both of smooth muscle tissues and skeletal muscle tissues. The heart is covered by a protective sac called the pericardium (Maton et. al., 1993). The pericardium itself is composed of two parts. The fibrous pericardium is made of dense fibrous connective tissue that serves as the heart’s outer protection while the serous pericardium contains fluid that eases friction generated by heart contractions thus protecting the heart from friction caused by its own beating (Maton et. al., 1993). The right atrium is situated on the right side of the heart where the veins carrying deoxygenated blood are found. This is so that the right atrium can collect the deoxygenated blood and pass it through the heart which pumps it by the right ventricle to the lungs to be oxygenated once more (Maton et. al., 1993). After the blood is oxygenated by the lungs, it goes back to the heart through the left atrium and is pumped by the heart through the left ventricle to the rest of the body. It should be noted that the muscle wall that surrounds the left ventricle is thicker than the wall surrounding the right ventricle. This is because it is harder to pump blood to the rest of the body than to just pump it to the lungs and back (Maton et. al., 1993). Hence, thicker muscle means that the left ventricle is more powerful in pumping blood than the right ventricle. Hypertensive heart disease   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   This diseases pertains to complications caused by arterial hypertension that affects the heart (eMedicine, 2007). Arterial hypertension which is more commonly known as high blood pressure is a condition wherein the pressure of the blood being pumped through the circulatory system is steadily increasing (eMedicine, 2007). This happens due to a variety of factors. Excessive intake of fat can clog up arteries and thus make it more difficult for blood to pass through. Thus, this makes the pressure of blood passing through the arteries increase. Because of the heightened pressure, the arterial walls are subjected to greater strain (Lip et. al., 2000). This can be imagined by visualizing a hose whose channel has been partially blocked. Fluid passing through that hose exerts more pressure on the hose walls and threatens to rupture the hose. In the same way, too much clogging in the arteries can cause pressure to build so much that it could ruptur e the arteries. Once this condition is elevated to dangerous levels, the heart gets affected by the imbalance in the pressure and hypertensive heart disease is developed (Lip et. al., 2000). The disease causes the heart to be strained more and more and may eventually cause it to breakdown and fail. The pressure can also burst blood vessels which can also damage the system. People suffering from this disease are easily fatigued due to the excessive work that the heart is coping with from the increased blood pressure (eMedicine, 2007). They would also have an irregular pulse, have difficulty sleeping, and feel a greater need to urinate at night (eMedicine 2007). If not treated with appropriate medicine, proper exercise and a good diet, hypertensive heart disease can lead death and is in fact one of the leading causes of death in the country (eMedicine, 2007). References De Graaff, V. (1998). Human Anatomy, 5th edition. WCB McGraw-Hill. Delos Johnson, D. (2006). The Circulatory System. Retrieved May 22, 2008 from: globalclassroom.org/hemo.html eMedicine. (2007). Hypertensive Heart Disease. Retrieved May 22, 2008 from: emedicine.com/med/topic3432.htm Hillendale Health. (2007). Circulatory System. Retrieved May 22, 2008 from: http://hes.ucfsd.org/gclaypo/circulatorysys.html Lip, G., Felmeden, D., Li-Saw-Hee, F., and Beevers, D. (2000). â€Å"Hypertensive heart disease. A complex syndrome or a hypertensive cardiomyopathy?† European Heart Journal. no. 21 p. 1653–1665. Hopkins, J., McLaughlin, C., Johnson, S., Warner, M., LaHart, D., and Wright, J. (1993). Human Biology and Health. New Jersey: Prentice Hall.

King George III Biography

King George III Biography George III was King of Great Britain and King of Ireland during the American Revolution. Much of his reign, which lasted from 1760 to 1820, was colored by his ongoing problems with mental illness. During the last decade of his life, he was incapacitated to the degree that his eldest son ruled as Prince Regent, giving name to the Regency Era. Fast Facts: King George III Full Name:  George William FrederickKnown For:  King of Great Britain and Ireland during the American Revolution, suffered from acute and debilitating bouts of mental illnessBorn:  June 4, 1738 in London, EnglandDied:  January 29, 1820 in London, EnglandSpouses Name: Sophia Charlotte of Mecklenburg-StrelitzChildren: 15 Early Years Born June 4, 1738, George William Frederick was the grandson of Great Britain’s King George II. His father, Frederick, the Prince of Wales, though estranged from the king, was still the heir apparent to the throne. George’s mother, Princess Augusta of Saxe-Goethe, was the daughter of a Hanoverian duke. Although sickly as a child- George was born two months prematurely- he soon grew stronger, and he and his younger brother Prince Edward moved with their parents to the family home in London’s exclusive Leicester Square. The boys were educated by private tutors, as was common for the children of royalty. Young George was precocious, and he could read and write several languages fluently, as well as discuss politics, science, and history, by the time he was an adolescent. Heritage Images / Getty Images In 1751, when George was thirteen, his father, the Prince of Wales, died unexpectedly, following a pulmonary embolism. Suddenly, George became the Duke of Edinburgh and the heir apparent to the British crown; within three weeks, his grandfather made him Prince of Wales. In 1760, George II passed away at the age of seventy, leaving 22-year-old George III to take the throne. Once he became king, he soon realized it was vital for him to find a suitable wife to bear his sons; the very future of the empire depended on it. Seventeen-year-old Sophia Charlotte of Mecklenburg-Strelitz was the daughter of a duke, privately educated, and had no scandals attached to her name, making her the perfect bride for a king. George and Charlotte did not even meet until their wedding day in 1761. By all reports, the two of them had a mutually respectful marriage; there was no infidelity on either of their parts, and they had fifteen children together. Charlotte and George were avid patrons of the arts, and were especially interested in German music and composers like Handel, Bach, and Mozart. During the first few years of Georges reign, the British Empire was financially shaky, due in part to the aftershocks of the Seven Years War (1756 to 1763). The British colonies were generating little revenue, so strict tax laws and regulations were enacted to bring extra money to the crown coffers. DEA / G. NIMATALLAH / Getty Images Revolution in the Colonies After decades of no representation in Parliament, and resentful of the extra tax burdens, the colonies in North America rebelled. Americas founding fathers famously detailed the transgressions perpetrated against them by the King in the Declaration of Independence: The history of the present King of Great Britain is a history of repeated injuries and usurpations, all having in direct object the establishment of an absolute Tyranny over these States.   After a series of setbacks in North America, Georges advisor Lord North, then the Prime Minister, suggested the king take a break from trying to handle the dissent in the colonies. North proposed that Lord Chatham, William Pitt the Elder, step in and take power of oversight. George refused the idea, and North resigned following General Cornwallis defeat at Yorktown. Eventually, George accepted that his armies had been defeated by the colonists, and authorized peace negotiations. Bettmann Archive / Getty Images Mental Illness and the Regency Wealth and status could not protect the king from suffering extreme bouts of mental illness- some so severe that he was incapacitated and unable to make decisions for his realm. George’s mental health issues were well-documented by his equerry, Robert Fulke Greville, and Buckingham Palace. In fact, he was heavily monitored by staff at all times, even while he slept. In 2018, the records were made public for the first time. In 1788, Dr Francis Willis wrote: â€Å"H.M became so ungovernable that recourse was had to the strait waistcoat: His legs were tied, he was secured down across his Breast, in this melancholy situation he was, when I came to make my morning Enquiries.† Scientists and historians have debated for over two centuries about the cause of the famous â€Å"madness.† One 1960s study indicated a link to the hereditary blood disorder porphyria. People suffering from porphyria experience acute anxiety, confusion, and paranoia. However, a 2010 study published in the Journal of Psychiatry concluded that George probably didn’t have porphyria at all. Led by Peter Garrard, professor of neurology at St. George’s University of London, researchers did a linguistic study of George’s correspondences, and determined that he suffered from â€Å"acute mania.† Many of the characteristics of George’s letters during his periods of illness are also seen in the writings and speech of patients today who are in the midst of the manic phase of illnesses like bipolar disorder. Typical symptoms of a manic state are compatible with contemporary accounts of George’s behavior. It is believed that Georges first bout of mental illness surfaced around 1765. He spoke endlessly, often for hours, and sometimes without an audience, causing himself to foam at the mouth and lose his voice. He rarely slept. He shouted unintelligibly at advisors who spoke to him, and wrote lengthy letters to anyone and everyone, with some sentences being hundreds of words long. With the king unable to function effectively, his mother Augusta and  Prime Minister Lord Bute  somehow managed to keep Queen Charlotte unaware of what was happening. In addition, they conspired to keep her ignorant of the Regency Bill, which decreed that in the event of George’s full incapacity, Charlotte herself would then be appointed Regent. Some twenty years later, after the Revolution had ended, George had a relapse. Charlotte was, by now, aware of the existence of the Regency Bill; however, her son, the Prince of Wales, had designs of his own on the Regency. When George recovered in 1789, Charlotte held a ball in honor of the Kings return to health- and deliberately failed to invite her son. However, the two of them formally reconciled in 1791. Although he remained popular with his subjects, George eventually descended into permanent madness, and in 1804, Charlotte moved into separate quarters. George was declared insane in 1811, and agreed to be placed under Charlottes guardianship, which remained in place until Charlottes death in 1818. At the same time, he consented to his empire being placed in the hands of his son, the Prince of Wales, as Prince Regent. Grafissimo / Getty Images Death and Legacy For the last nine years of his life, George lived in seclusion at Windsor Castle. He eventually developed dementia, and didnt seem to understand that he was the king, or that his wife had died. On January 29, 1820, he died, and was buried a month later at Windsor. His son George IV, the Prince Regent, succeeded to the throne, where he reigned for ten years until his own death. In 1837, Georges granddaughter Victoria became Queen. Although the issues addressed in the Declaration of Independence paint George as a tyrant, twentieth-century scholars take a more sympathetic approach, viewing him as a victim of both the changing political landscape and his own mental illness. Sources â€Å"George III.†Ã‚  History.com, AE Television Networks, www.history.com/topics/british-history/george-iii.â€Å"What Was the Truth about the Madness of George III?†Ã‚  BBC News, BBC, 15 Apr. 2013, www.bbc.com/news/magazine-22122407.Yedroudj, Latifa. â€Å"Mad King George III Mental Health Records REVEALED in Buckingham Palace Archives.†Ã‚  Express.co.uk, Express.co.uk, 19 Nov. 2018, www.express.co.uk/news/royal/1047457/royal-news-king-george-III-buckingham-palace-hamilton-royal-family-news.

China as a super power Term Paper Example | Topics and Well Written Essays - 1500 words

China as a super power - Term Paper Example On March 4, 2007, China announced that it was going to increase its military to a total of 45 billion dollars (Tkacik, 2007). This was the biggest annual increase in China’s military budget; however, China was quick to reassure the world that there was no need to worry by calling the increment normal. A further look into this increment indicated that China has an intention to challenge the United States’ military supremacy. This could lead to a situation where China is the United States’ single competitor with regard to influence and military supremacy. China’s air force and space activity is on the rise. The army in China has got roughly 300 Russian fourth generation flankers; it has also got several homemade Jian-11 planes and 76 Sukhoi multi-role fighter jets. Russia and Israel assisted the Chinese air force in procuring 50 Jian-10 fighter jets. These jets were based on the United States F-16 technology. China has intentions to build more of these plane s. China has increased its production and deployment of the short-range ballistic missiles which are said to be aimed at Taiwan. This production has grown from 50 per year in 1990s to 150 missiles annually today. The industries that produce such missiles in China are said to grow at the same pace. In general, China’s rocket soldiers and its air force are expanding at an unprecedented pace. According to China’s 2006 White Paper, there is evidence that China is moving to offensive. This military might of China is growing from regional to trans-regional mobility. The air to ground military capacity has also grown, including long distance maneuvers and exceptional operations. The Chinese navy has grown in strength into a force that can operate in the maritime operations and can ably handle nuclear counterattacks. The Chinese air force has continued to increase its capabilities to strike, tried to procure air and missile defense shield systems and is looking into more offen sive and defensive operations. All these are an early warning shot of the Chinese reconnaissance. According to a report by Congress, China’s policy is now global and extremely bold. China has always been underrated and many times the United States said that China has not acquired the status of a super power. Thomas Jefferson, at the beginning of the nineteenth century, observed that the United States had to trade all over the world if it had to become a global power economically. Beijing’s assessment is that it has grown to the extent that its economic growth depends on foreign markets. This also includes the natural resources from other countries around the world. China‘s economy has been growing rapidly, and China is seeking military might that can protect this growth. This is similar to Jefferson’s observation that the United Stated had to build its military strength if it was to safeguard its military strength globally. It seems that the rise of the Pe ople’s Republic of China is both legitimate and inevitable (McLean, 2007). However, according to Condoleezza Rice, the former Secretary of State of the United States, the US needs to help China operate within the international rules framework before it has fully acquires the status of a military super power. Many view the rise of China as an exceedingly dangerous happening. Why does Bleicher think the fears are overblown? According to Samuel Bleicher, the idea that China is an emerging super power is a creation of the media. He believes s that

International Money and Finance (Final stage 3) Essay - 2

International Money and Finance (Final stage 3) - Essay Example The company’s annual report 2010 provides clues on the exchange rate risks. Operating Statistics Number of rental stores Staff numbers 31 October 30 April 31 October 30 April 2010 2009 2010 2010 2009 2010 Sunbelt Rentals 346 397 393 5,373 5,733 5,334 A-Plant 104 111 105 1,876 1,944 1,872 Corporate office - - - 11 12 12 Group 450 508 498 7,260 7,689 7,218 The operating statistics on the number of rental stores and staff strength provide a comparative view of the performance of the Ashtead Group in the years 2009 and 2010 respectively in Sunbelt Rentals and A-Plant (Ashtead Group Press Release, 2011). Exchange Rate Risk Ashtead Group is exposed to exchange rate risk developed from translation risk emerging from most of the company assets, liabilities, income and costs written in the US dollars. The changes in the comparative value of Pound Sterling and the US dollar can impact on the financial strength and functioning of the company. All debt of the company is shown in the US do llars to secure to a certain extent the revenue stream, hedging against the translation effects erupting from the shift in the dollar exchange rate. The company pays dollar interest on its debts to reduce the impact of any shift in the dollar exchange rate on its income (Ashtead Group Annual Report Accounts, 2010). Movements in the rate of the US dollar with respect to Pound Sterling has been having and crucial impact on our financial position and outcomes of operations as registered in pounds are because most of the company assets, liabilities, income and costs are represented in US dollars. Movement in the exposure of the firm against Pound Sterling or other currencies however, can create significant transaction exposure for the firm. Higher level of exposure can affect the firm’s short term cash flows and therefore may force the firm to borrow to meet its short term cash requirements. (Moffett, Stonehill, & Eiteman,2009). Till 31 October 2010 all company debts shown in the US dollar were nearly 80% of the value of net assets shown in dollar. It proved out to be robust hedge against currency fluctuations. It reduces the impact of exchange rate fluctuations as interest is paid through dollar as well, thus, reducing the effect on pre-tax profits and income. Based on the latest currency mix of Ashtead Group’s profits and on dollar debt levels, interest and exchange rates at 31 October 2010, a 1% change in the US dollar exchange rate would impact pre-tax profit by ?40,000 (Ashtead Group Press Release, 2011). The company has been benefitting from the strong dollar in the past, as is evident from the results of Sunbelt from stronger dollar in the year 2009 when revenues in dollar were short by 21% across the year to US$1450 million but in reality increased by 7% when shown in UK sterling (International Rental News, 2009). Ashtead's Sunbelt results were boosted by the stronger dollar. Sunbelt's revenues in dollars fell by 21% over the year to US$1450 million, although actually grew by 7% when expressed in UK sterling. A-Plant's sales for the year fell by 2% to 208.0 [pounds sterling] million. Dollar exchange rate hedging worked well for the company in the year 2009 amidst reducing sales for both the companies of the group in the final quarter with 28% cut in income by A-Plant and 24% reduction in the income of Senbelt in local

Compulsive Gambling Essay Example for Free

Compulsive Gambling Essay More than 5 million Americans are pathological, compulsive and problem gamblers, and another 15 million are at risk of becoming just like them. A common definition of problem gambling is: a progressive disorder characterized by a continuous or periodic loss of control over gambling and irrational thinking and behavior despite the consequences. When gambling interferes with any ones life, it can be categorize as an addiction or disease, just like alcohol and drug addiction is categorize as a disease. A study conducted for the National Gambling Impact Study Commission found that 20 million American have or could develop gambling problems. Also they have estimated those 1. 8 million American adults as well as up to 1. 1 million American adolescents age 12 through 17 engage in severe pathological gambling each year. As legalize gambling has become more common in the United States; problems have sprung up as well. That negative influence is becoming more apparent as gambling is more widely available. It is becoming increasingly easy to gamble in the United States particularly in the last 10 years, and problems with gambling are much more common now than they ever were. Studies show that for every dollar gambling produces for a regional economy, three dollars are lost because of the economic and social cost of gambling. The study has also said that if the government legalizes more gambling, taxpayers will lose money, whether they gamble or not. The gambling industry believes it is just selling an innocent form of family entertainment, but they dont mention how much the players lose or how gambling encourages addictive behavior or the enormous costs it creates for the rest of society. It has been said that, gamblers with higher counts of gambling symptoms will have higher rates of problem. There many consequences associated with compulsive, pathological and problem gamblers. Examples of such consequences include job and financial problems, divorce, poor health, and criminal involvement. These addictions are the lifeblood of the gambling industry, said an economist from the University of Illinois by name Earl Grinols. He researches and found out, that casinos earn more than half their revenues from compulsive, pathological, and problem gamblers. The casino industry is heavily dependent on the revenues of psychologically sick people, says Grinols. Millions of families are paying a heavy price, not just financially, but also strains in family and marital relationship. Family members of compulsive and pathological gamblers are hurt by their disease, mainly because an emotional withdrawal occurs, which leads to separation.

Essays --

The Ethics of Drug Design and Testing Victor Arce Arizona State University â€Æ' Drug Design, Testing, and Marketing The discovery of a lead pharmacophore and its subsequent testing in animals and humans has only recently taken shape thanks to the advancement in the fields of pharmacology, physiology, chemistry, and biology. Within the last 40 years, the near-linear advancement of computing power has allowed for the imaging of enzyme structures and therefore led to the ab initio calculations of structure shape and size in drug development. The recent scientific interest in biomimicry has created a new field for lead drug synthesis and treatment. The field of pharmacology is being bombarded with possible drug targets so why has the influx of drugs into the market remained relatively slow compared to all of the possible leads? The answer to that question has to do with the process by which a drug must be tested and approved before hitting markets. The process by which a treatment or a drug is studied is scientific. Figure 1- A flowchart demonstrating the process by which a drug must undergo before being marketed and regulated to the public. Figure 1 shows the process by which a drug is developed. The basis of therapies lies in the chemical, physiological understanding of disease. The study begins with a question. The question or hypothesis is based on the understanding of the human body and it’s function. The hypothesis must then be tested using reproducible methods. The compound in question is tested in vitro using a line of cells that are most relevant to the target site that the researchers are studying. For example, if you are researching a drug that could possibly target lymphomas, you would use a cell line that ... ...standard for human research ethics. The document is not legally binding to any country or entity but instead serves as a moral standard for all scientists and physicians as well as countries who want to use it as a guideline for legislation on human research in their own jurisdiction. Conducting Ethical Animal Research As seen in the first part of this paper, the use of animals in the advancement of medical knowledge can be traced back to the Romans. Galen may be one of the first historically significant scientists who used animals to further the knowledge of medicine. His vivisections led to a greater understanding of the healing process, the cardiovascular system, and digestion among other topics. By today’s standards, the vivisections that Galen carried out are seen as unethical and barbaric. The unnecessary level of pain inflicted on the animal would today be Essays -- The Ethics of Drug Design and Testing Victor Arce Arizona State University â€Æ' Drug Design, Testing, and Marketing The discovery of a lead pharmacophore and its subsequent testing in animals and humans has only recently taken shape thanks to the advancement in the fields of pharmacology, physiology, chemistry, and biology. Within the last 40 years, the near-linear advancement of computing power has allowed for the imaging of enzyme structures and therefore led to the ab initio calculations of structure shape and size in drug development. The recent scientific interest in biomimicry has created a new field for lead drug synthesis and treatment. The field of pharmacology is being bombarded with possible drug targets so why has the influx of drugs into the market remained relatively slow compared to all of the possible leads? The answer to that question has to do with the process by which a drug must be tested and approved before hitting markets. The process by which a treatment or a drug is studied is scientific. Figure 1- A flowchart demonstrating the process by which a drug must undergo before being marketed and regulated to the public. Figure 1 shows the process by which a drug is developed. The basis of therapies lies in the chemical, physiological understanding of disease. The study begins with a question. The question or hypothesis is based on the understanding of the human body and it’s function. The hypothesis must then be tested using reproducible methods. The compound in question is tested in vitro using a line of cells that are most relevant to the target site that the researchers are studying. For example, if you are researching a drug that could possibly target lymphomas, you would use a cell line that ... ...standard for human research ethics. The document is not legally binding to any country or entity but instead serves as a moral standard for all scientists and physicians as well as countries who want to use it as a guideline for legislation on human research in their own jurisdiction. Conducting Ethical Animal Research As seen in the first part of this paper, the use of animals in the advancement of medical knowledge can be traced back to the Romans. Galen may be one of the first historically significant scientists who used animals to further the knowledge of medicine. His vivisections led to a greater understanding of the healing process, the cardiovascular system, and digestion among other topics. By today’s standards, the vivisections that Galen carried out are seen as unethical and barbaric. The unnecessary level of pain inflicted on the animal would today be

Aeeta Riddles

The first one was written by the Etas language and followed by an English translation. The answer key follows: 1. Multimedia It wears a crown but isn't a queen It has scales but isn't a fish. 2 . Cassini nag pià ±atas in Pap Nag mismanage you lulu an? There Is a cave with a bolo In It Full of bones It Isn't a grave. 3. Ajar Tanganyika nag nick Away Piccalilli. When you cut it It is mended without a scar. 4. Appeal Gait Awn an did maillot. The thigh of Gatherer all scrape at. 5. Bulgarian aka Agenda Lilliputian mammal. Black stone at Agenda, surrounded by little fishes. 1 OFFThis creature never leaves unless he brings his home. 7. Nu baby ay canvassing; nu areola ay mammalian. It is noisy when shallow, and silent when deep. 8. Nu Babylonian ay embedded. If I open it, it gossips. 9. You Anza y gaff an capacity an nanas. The child is the cause of his mother's death. 10. Nu gaff eBay, nu aha totals Sea by night, tube by day. 1 1 . Nu maturated, attendant, nu metadata, phobia. Standing i t is short, sitting it is tall. 12. Ana data sinology name Mikado nu mature. There's a creature that does not close its eyes when asleep. 13. Incur sauna, manmade Anatolia.If he says he goes, he means he comes. 14. Goanna nu using y mama; managerial pay sill y mina. If you pull your daddy's penis, your mommy's vagina screams too. 15. Cabana you nag an; nasals-assist you Allan an. Inside is full of stones, outside is full of thorns. 16. Titian is canny; dude meme Maida-tit. You stare at it often, yet you never have seen it. 17. Citation SE gaffing; Inca SE anion. Come now, it is dark; go now, it's dawn. 18. Immaculate-latte, mean macaroon. It Jumps and Jumps but cannot move out of its place. 19. Nu manure ay mallow, nu unanimous ay maybug.If it comes it's slow, if it goes up, it's fast. 20. Asana way packet data queue lag. 21 . Is like a managing, ambulated; cabling cue managing, amphibians. Before meals, I am full, after meals I am hungry. ANSWERS 1. Pippin (Pineapple) Simi ( Mouth) 2. 3. Datum (Water) 4. Honey 5. Mortar 6. Adage (turtle) mahatma (river) 7. 8. Bionic (fan) 9. Baht (bananas) 10. AFC (mat) 11. Tat (dog) 12. Durum (grasshopper) 13. Load (shrimp) 14. Company (bell) 15. Imaging Kiwifruit) 16. Sinai (sun) sawing (window) 17. Making (sewing machine) 18. 19. Duggan (booger) 20. Cop (cup) 21 . Caldera (kettle, pot) 1.Mandamuses A instantiating. There is a cave with a bolo in it Full of bones it isn't a grave. Away piccalilli. The thigh of Gait, where all scrape at. 6. Ion sinology, name manna nu name, pan ion bally an. There's a creature that does not close its eyes when asleep. 13. Incur sauna, gammed Anatolia. If you pull your daddy's penis, your mommy's vagina screams too. Inside is full of stones, outside is full of thorns. 16. Titian is canny; dude meme Maida-tit. It Jumps and Jumps but cannot move out of its place. 19. Nu manure ay mallow, nu unanimous ay maybug. Who is he that has but one ear?